Owen Chan, MD, PhD

Owen Chan, MD, PhD

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Director, Pathology Core Shared Resource, University of Hawaiʻi Cancer Center
Associate Member, Cancer Biology, University of Hawaiʻi Cancer Center
Core Clinical Member, Translational and Clinical Research, University of Hawaiʻi Cancer Center

Academic Appointment(s):
Assistant Researcher (Assistant Professor), Translational and Clinical Research, University of Hawaiʻi Cancer Center
Assistant Clinical Professor, Department of Pathology, John A. Burns School of Medicine, University of Hawaiʻi

Degree(s):
MS, Biology and MPhil, Biology, Yale University, New Haven, CT
PhD, Immunobiology, Yale University, New Haven CT
MD, John A. Burns School of Medicine, University of Hawaii, Honolulu, HI
Postdoctoral Fellowship, Immunology, University of California, San Francisco, CA
Placental Pathology Fellowship, University of California, San Diego, CA
Combined Anatomic Pathology / Clinical Pathology Residency, University of California, San Diego, CA
Hematopathology Fellowship, Stanford University, Stanford, CA
Gastrointestinal/Liver Pathology Fellowship, Cedars-Sinai Medical Center, Los Angeles, CA

Research Focus

I am interested in translational research, especially as it pertains to the tumor inflammatory microenvironment. Currently, I collaborate with multiple members of the University of Hawaiʻi Cancer Center, where I utilize my training as a pathologist and basic science researcher. I also serve as the Director of the Pathology Shared Resource.

Selected Publications

Kwee SA, Wong L, Chan OTM, Kalathil S, Tsai S. (2018). PET/CT with 18F Fluorocholine as an Imaging Biomarker for Chronic Liver Disease: A Preliminary Radiopathologic Correspondence Study in Patients with Liver Cancer. Radiology, April; 287(1): 294-302. PMID: 29315063.

Shimizu Y, Furuya H, Tamashiro PM, Iino K, Chan OTM, Goodison S, Pagano I, Hokutan K, Peres R, Loo LWM, Hernandez B, Naing A, Chong CDK, Rosser CJ, Kawamori T. (2018). Genetic deletion of Sphingosine Kinase 1 suppresses mouse breast tumor development in a HER2 transgenic model. Carcinogenesis, January 12; 39(1):47-55. PMID: 28968647.

Chan OTM, Furuya H, Pagano I, Shimizu Y, Hokutan K, Dyrskjøt L, Jensen JB, Mamstrom PU, Segersten U, Janku F, Rosser CJ. (2017). Association of MMP-2, RB and PAI-1 with decreased recurrence-free survival and overall survival in bladder cancer patients. Oncotarget, September 6; Vol. 8(59): 99707-99721. September 6, 2017. PMID: 29245935.

Furuya H, Shimizu Y, Tamashiro PM, Iino K, Bielawski J, Chan OTM, Pagano I, Kawamori T. (2017). Sphingosine kinase 1 expression enhances colon tumor growth. J Translational Medicine, Vol. 15(1):120; June 6. PMID: 28583134.

Okimoto GA, Zeinalzadeh T, Wenska M, Loomis JB, Nation T, Fabre M, Tiirikainen M, Hernandez B, Chan O, Wong L, Kwee S. (2016). Joint analysis of multiple high-dimensional data types using sparse matrix approximations of rank-1 with applications to ovarian and liver cancer. BioData Mining, Vol. 9:24. July 29. PMID: 27478503.

Publication list via PubMed